6th Annual BTOG Meeting 2008
Venue: Clontarf Castle Hotel, Clontarf, Dublin 3, Republic of Ireland
Wednesday 23rd to Friday 25th January 2008
Continuing Professional Development - Total 15 CPD Credits
Awarded by the Royal College of Physicians, London
Programme in collaboration with
IASLC All Ireland Lung
Cancer Forum
Irish Lung Cancer Nurses Group
Wednesday 23rd January 2008 - The Great Hall 1
BTOG Symposium
3 CPD Credits awarded by the Royal College of Physicians
10:30 am Registration & Refreshments - The Great Hall Foyer
Session 1 Applying Technology to Patient Diagnosis, Prognosis and Treatment
Chair:
Mike Lind (UK)
11:00 am Transcriptomic profiling for diagnosis
Joe Keane (IRL)
11:20 am ALMAC transcriptome wide RNA extraction from
paraffin-embedded tissue
Richard Kennedy (UK)
11:40 am Micro-inhibitory RNA in thoracic oncology
John O麓Leary (IRL)
12:00 pm Epigenetics John Field (UK)
Panel discussion
12:30 pm Soup and Sandwich Lunch - The Great Hall 2
Session 2 Concept of Tumour Vulnerability
Chair:
David Gilligan (UK)
1:00 pm Predictors of sensitivity to chemotherapy
Mark Kris (USA)
1:20 pm Markers of radiosensitivity/resistance
Craig Stevens (USA)
1:40 pm Microarray approaches to predictor identification Keith Kerr (UK)
2:00 pm Imaging therapy interactions at the molecular level Tony Ng (UK)
2:20 pm Apoptosis as a pharmacodynamic endpoint
Dean Fennell (UK)
2:40 pm Registration - The Great Hall Foyer and Refreshments - The Great Hall 2
Wednesday 23rd January 2008 - The Great Hall 1
3:00 pm to 7:40 pm
Sponsored Satellite Symposia
Transport at 8:00 pm to Dinner
Supported by an unrestricted educational grant from Merck Sharp & Dohme
3.00 pm Is Chemotherapy Induced Nausea and Vomiting a Thing of the Past?
Chair:
David Ferry (UK)
Cisplatin coming or going? Ken O'Byrne (IRL)
ASCO guidelines on antiemetics 2006 revision
Mark Kris (USA)
Case studies David Dunlop (UK)
4:00 pm Close
Supported by an unrestricted educational grant from Roche
4:10 pm Debate: This House Believes There is Good Evidence to
Select Patients with EGFR Inhibitors
Chair:
Ethan Lyn (UK)
For:
Simon Grumett (UK)
Against: Gary Middleton (UK)
5:10 pm Close
Supported by an unrestricted educational grant from Lilly
5:30 pm
The Evolution of Thoracic Cancers
Chair:
Peter Harper
5:30 pm Chairman's introduction
5:35 pm Achieving more in the treatment of malignant
pleural mesothelioma Rolf Stahel (EUR)
6:00 pm Treatment of NSCLC: new considerations
Nick Thatcher (UK)
6:30 pm Close
Supported by an unrestricted educational grant from sanofi-aventis
6:40 pm Challenging Assumptions in Advanced NSCLC
Chair:
Marianne Nicolson
6:40 pm Introduction
6:45 pm Optimising chemotherapy for advanced NSCLC Mark Kris (USA)
7:10 pm Optimising the management of advanced NSCLC in
today's NHS David Thomson (UK)
7:25 pm The UK experience in the management of advanced
NSCLC
Marianne Nicolson (UK)
7:35 pm Panel Discussion / Questions & Answers
7:40 pm Close
8:00 pm Coach Transport to Dinner from Clontarf Castle Hotel
The 16th Century Abbey Tavern is located in Howth and gives a real warm
welcome, blazing turf fires, original stone walls, flagged floors and gas lights. A 4
course Irish dinner finishing with Irish coffee will be served before a lively
performance of music, song and Irish dance. This evening is a must for anyone
wanting to experience a traditional Irish night during their time in Dublin. A small
nominal charge of 拢20 or 30 euros applies.
Thursday 24th January 2008 - The Great Hall
8:30 am to 9:00 am
Satellite Meeting - From Clinical Evidence to Practice
Supported by an unrestricted educational grant from Pierre Fabre
Chair:
David Dunlop
8:30 am Minimising haematological consequences of platinum
doublets in advanced NSCLC
Ulf Aaseb 0 (NwY)
Navelbine Oral in trial and practice
Mary O'Brien (UK)
9:00 am Close
Thursday 24th January 2008 - The Great Hall
6th Annual British Thoracic Oncology Group Meeting 2008
6 CPD Credits Awarded by the Royal College of Physicians
9:10 am
Opening of the BTOG Annual Meeting
Issues in diagnostic evaluation and treatment of
thoracic malignancies
Ken O麓Byrne (IRL)
Session 1 General Issues in UK Thoracic Oncology
Chairs:
Tim Eisen (UK) & David Dunlop (UK)
9:20 am The National Lung Cancer Audit (LUCADA):
patients, treatment and outcomes
Mick Peake (UK)
9:35 am Gaps in NCRI programme
00Radiation oncology studies
Ethan Lyn (UK)
00Surgical oncology studies David Waller (UK)
9:55 am
Lung cancer biobank: can we learn from Spain
Noemi Reguart (EUR)
10:10 am What would make the ideal UK lung cancer trial? Cindy Billingham (UK)
Panel discussion
10:45 am Refreshments and Exhibition - Viking Suite
Posters - Great Hall Foyer & Mezzanine Levels 1, 2 & 3
Session 2 Epidermal Growth Factor Receptor Overview
Chairs:
Penella Woll (UK) & Wilfred Eberhardt (EUR)
11:15 am EGFR targeted therapies overview
Robert Pirker (EUR)
11:30 am EGFR mutations, FISH and IHC:
prognostic and/or predictive factor?
Thomas Lynch (USA)
11:45 am EGFR proteomics David Carbone (USA)
12:00 pm EGFR resistance mechanisms: clinical implications Pasi J盲nne (USA)
12:30 pm IGFR1 in NSCLC
Luis Paz-Ares (EUR)
12:45 pm Panel discussion
1:00 pm Lunch and Exhibition - Viking Suite
Posters - Great Hall Foyer & Mezzanine Levels 1, 2 & 3
Session 3 Mesothelioma
Chairs :
Rolf Stahel (EUR) & Martin Muers (UK)
2:00 pm Nursing perspective in mesothelioma
Liz Darlison (UK)
2:15 pm Biomarkers in mesothelioma Harvey Pass (USA)
2:35 pm Is there a radical operation or is it debulking?
John Edwards (UK)
2:55 pm Systemic therapy: where are we and where to go?
Sjaak Burgers (EUR)
3:15 pm Discussion
3:45 pm Refreshments and Exhibition - Viking Suite
Posters - Great Hall Foyer & Mezzanine Levels 1, 2 & 3
4:00 pm Workshops - Great Hall 1, 2 & Dalcassion 5:30 pm Close
Workshop 1 - Great Hall 1
Systemic Therapy for Advanced Disease
Chairs: David Ferry (UK) & Marianne Nicolson (UK)
BTOG-2 update on trial recruitment and assessing Hugh Jarrett (UK)
the blocks in running a successful randomised trial
in the UK and Ireland after enactment of the
EU directive
Can we use ERCC1 status to define which patients Siow Ming Lee (UK)
will benefit from non-platin based chemotherapy?
Is thymidylate synthase inhibition a useful strategy
David Ferry (UK)
in advanced NSCLC?
Workshop 2 - Great Hall 2
Nursing Issues
Chairs: Maria Guerin (UK) & Liz Darlison (UK)
4:00 pm
Welcome
Liz Darlison (UK)
4:05 pm The lived experience of patients with mesothelioma Nicki Hughes (UK)
4:25 pm NLCFN/Lilly Workshop Project 1
A retrospective audit: does the lung cancer CNS
Nicola Bell (UK)
reduce unplanned hospital admissions?
4:40 pm NLCFN/Lilly Workshop Project 2
Key elements: the lung CNS role
Gillian Walton (UK)
4:55 pm Pandora's update
Alison Leary (UK)
5:15 pm Questions
Workshop 3 - Dalcassion
BMIG/NCRI Mesothelioma Sub Group/NCRI LORD Subgroup
Surgical Trials in Mesothelioma and NSCLC
Chairs: Tom Treasure (UK) & Harvey Pass (USA)
4:00 pm MARS-2: The next frontier - inclusion of radical
Pleurectomy/Decortication?
John Edwards (UK)
4:20 pm MesoVATS: update and the future with MARS-2 Robert Rintoul (UK)
4:40 pm Surgery vs Radiotherapy trial in high risk
David Waller (UK) &
stage I NSCLC
Matthew Hatton (UK)
5:10 pm Discussion, other trial ideas
Feedback and outcomes from the Workshops will be collated by the Workshop
Chairs and included in the post-meeting BTOG Newsletter.
7:00 pm Wine Reception - Clontarf Castle Reception and the Great Hall Foyer
Posters - Great Hall Foyer & Mezzanine Levels 1, 2 & 3
8:00 pm BTOG Annual National Meeting Dinner Dance - The Great Hall
including Special Achievement Award presentation
Friday 25th January 2008 - The Great Hall
8:00 am to 9:00 am
Satellite Meeting - Pfizer and Irish Cancer Society
Supported by an unrestricted educational grant from Pfizer
Chairs: John McCormack (IRL) & Mick Peake (UK)
8:00 am Strategies for lung cancer chemoprevention
Norma Cronin (IRL)
8:25 am The role of Champix in smoking cessation
Ken O'Byrne (IRL)
9:00 am Close
Friday 25th January 2008 - The Great Hall
6th Annual British Thoracic Oncology Group Meeting 2008
6 CPD Credits Awarded by the Royal College of Physicians
Session 4 Symptom Control
Chairs:
Liam O麓Siorain (IRL) & Finbarr O麓Connell (IRL)
9:10 am Lung cancer cachexia - A difficult clinical problem Robert Milroy (UK)
9:25 am Recent advances in mechanism-based pain control Sam Ahmedzai (UK)
9:40 am Erythropoietin in non-small cell lung cancer?
Harry Raftopoulos (US)
10.00 am Nursing issues: the wider picture
Maria Guerin (UK)
10:15 am Management of cancer associated depression
Anne-Marie O麓Dwyer (IRL)
10:30 am Discussion
10:45 am Refreshments and Exhibition - Viking Suite
Posters - Great Hall Foyer & Mezzanine Levels 1, 2 & 3
Session 5 BTOG/BTS/AILCF Symposium
Staging of Lung Cancer: Implications for Therapy
Chairs: David Baldwin (UK) & James Entwisle (UK)
11:15 am Non-small cell lung cancer
Peter Goldstraw (UK)
11:45 am Small cell lung cancer
Des Carney (IRL)
12:00 am Molecular Biological Staging
00MicroRNA
Nico Van Zandwijk (EUR)
00Proteomics David Carbone (USA)
12:30 pm Radiological Staging
Fergus Gleeson (UK)
12:45 pm Panel discussion
1:00 pm Lunch and Exhibition - Viking Suite
Posters - Great Hall Foyer & Mezzanine Levels 1, 2 & 3
Session 6 Small Cell Lung Cancer
Chairs:
Eric Lim (UK) & Paul Lorigan (UK)
2:00 pm Outcomes for screen detected SCLC patients
Claudia Henschke (USA)
2:15 pm Chemotherapy for SCLC: Where are we?
Fiona Blackhall (UK)
2:30 pm Issues for radiotherapy
Corinne Faivre-Finn (UK)
2:45 pm Targeted therapies Vera Hirsh (CA)
3:00 pm Discussion
3:15 pm Refreshments and Exhibition - Viking Suite
Posters - Great Hall Foyer & Mezzanine Levels 1, 2 & 3
3:30 pm Workshops - Great Hall 1, 2 & Dalcassion 5:00 pm Close
Workshop 1 - Great Hall 1
BTOG/NCRI LORD Subgroup
Chairs: Matthew Hatton (UK) & Denis Talbot (UK)
3:30 pm Introduction Matthew Hatton (UK)
3:35 pm Radiotherapy
Current trial proposals: IDEAL
3:40 pm CHART - ED Matthew Hatton (UK)
3:45 pm NORCOR-1
3:50 pm Discussion and feedback from centres regarding
Matthew Hatton (UK)
recruitment for UK lung XRT research
4:15 pm Adjuvant studies: background
Denis Talbot (UK)
4:25 pm Current trial proposal: aspirin
Mike Poullis (UK)
4:35 pm Discussion: considering the need for future meeting Denis Talbot (UK)
specifically to develop ideas/protocol in this area
Workshop 2 - Great Hall 2
BTOG/NCRI (SCEPTRE* subgroup)/BTS/UK Respiratory Research
Collaborative (* S moking CE ssation P revention s TR ategies and E arly diagnosis)
Developing Collaborative Research Programmes and Infrastructure
Chairs: Mick Peake (UK) & Robert Rintoul (UK)
3:30 pm Introduction and background - the UK Respiratory
Research Collaborative and other initiatives on
earlier diagnosis
Mick Peake (UK)
3:45 pm Update on the UK screening trial
4:00 pm The Lung-SEARCH trial Robert Rintoul (UK)
4:10 pm Ideas for a UK study on pulmonary nodules David Baldwin (UK)
4:25 pm Open discussion - how to get 'quick wins' and sustainable capacity
Workshop 3 - Dalcassion
NCRI CSG Translational Research
Chair:
John Field (UK)
3:30 pm E T study
Siow Ming Lee (UK)
3:45 pm Study 12: thalidomide trial in SCLC &
Study 14: thalidomide in NSCLC
Siow Ming Lee (UK)
4:00 pm Predictive epigenomics derived from circulating
Plasma DNA in NSCLC
Peter Schmid (UK)
4:15 pm Scottish Erlotinib Lung Cancer Project (ScELP)
4:30 pm TRANSMATIC
4:45 pm UK Lung Cancer Consortium (UKLCC) - Proposal John Field (UK)
Feedback and outcomes from the Workshops will be collated by the Workshop
Chairs and included in the post-meeting BTOG Newsletter.
5:00 pm Close of the 6th Annual BTOG Meeting 2008
download Wednesday 23rd January 2008 - The Great Hall 1 BTOG Symposium 3 CPD ...
